Biomolecular Condensates in Cancer

27 - 30 Jan 2022Add To Calendar
Asilomar Hotel and Conference Grounds, Monterey, USA
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Danfeng Cai, PhD, HHMI Janelia Research Campus Alex Holehouse, PhD, Washington University in St. Louis Tanja Mittag, PhD, St. Jude Children’s Research Hospital. A number of specific cancers are directly linked to proteins we now know can form biomolecular condensates. These LCDs are necessary and su cient to drive phase separation, and in a number of different cancers these LCDs translocate to oncogenic DNA binding domains, driving malignancy. At the level of gene regulation, super-enhancers .. continue reading are biomolecular condensates that occupy specific loci on the genome and drive high-level constitutive transcription. Recent work suggests that super-enhancers form through phase separation, and that their formation at oncogenes may be a common mechanism through which transcriptional upregulation occurs in transformed cells. The Foundation can only accommodate 1 pick up per day at San Jose. The Foundation can only accommodate 1 pick up per day at San Francisco.


09:00 AM-06:00 PM (expected)
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upto 100
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Medical & Pharma


Jan 2022 Interested
+1 more edition

Frequency Annual

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William Guy Forbeck Research Foundation

USA9 Total Events / 4 Upcoming Events

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