Cellular Reprogramming and Metastatic Disease

We propose to explore current understanding of the molecular mechanisms that allow cancer cells to leave the primary site, disseminate, and grow as metastatic disease in
a foreign tissue. We will also explore how these cells avoid/resist treatment as part of such metastatic disease progression. New knowledge suggest that beyond genetic mutations, cancers cells may acquire non-genetic adaptations (metabolism, epigenetics, cell cycle resistor phenotypes, immune modulation) that could confer .. continue reading unique advantage to these aggressive cells. We plan to discuss new models to study metastatic disease, and current state of affairs in the field. The abstracts should be only one or two paragraphs outlining the theme of your presentation and should reflect the objective and spirit of the meeting (see above). Abstracts will be circulated about one week before the meeting. The meeting organizer will start requesting them a month before the meeting.