Challenges and Successes in Externalization of the ADC Supply Chain is further complicated by the fact that there is not one contract facility that .. Read more has fully integrated services, a one-stop shop capable of mAb production, linker and/or payload synthesis, conjugation of mAb to linker-payload to make the Drug Substance, and finally, formulation of the ADC to make the Drug Product. Strategizing the best outsourcing practices for producing and testing ADCs, and establishing guiding principles for externalization to ensure the selection of the right CMOs for ADC outsourcing and technology transfer, will be further discussed.
Firelli Alonso, Ph.D.Senior Director, External Supply at Pfizer
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