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27 Oct 2020  • 

Quantitative transmission Raman for content uniformity testing

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27 Oct 2020

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In this webinar, development groups will learn how analysis with quantitative transmission Raman aids in formulation development and process .. Read more development, by non-destructively measuring tablets with low dosage levels (down to 0.1% percent API) and distinguishing polymorphs. Raman spectroscopy is a valuable analytical tool for verifying quality from incoming material to final product testing. Non-destructive analysis with transmission Raman spectroscopy is a rapid method to measure the concentration of the active pharmaceutical ingredient (API) and excipients with one single test. With transmission Raman, the measurement is done across the sample volume, giving representative tablet analysis, and not just on the surface. In this webinar, development groups will learn how analysis with quantitative transmission Raman aids in formulation development and process development, by non-destructively measuring tablets with low dosage levels (down to 0.1 percent API) and distinguishing polymorphs. Quality control (QC) groups will see how Raman both accelerates testing by cutting analysis time down to a minute and saves costs by reducing the quantity of solvent, waste and maintenance required compared to traditional HPLC analysis. Development and QC benefit from transmission Raman to provide the tablet content and polymorphic form of samples without requiring sample preparation, thus minimising the test preparation and testing time, and waste generation.

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