Join this free webinar to learn more about Target Safety Assessments and how they can lead to a reduction in safety-related attrition in drug .. Read more projects. At least 50 percent of drug safety failures are attributable to target-related effects. So, it makes sense to understand potential safety liabilities associated with a target early in projects, in order to anticipate and manage those issues before they arise. A target safety assessment (TSA) brings together public domain information (target homology, gene and protein expression profiles, transgenic and mutation phenotype data, competitor compounds) into a report that identifies and categorizes key risks by organ/tissue and by physiological functions. Join this educational webinar to learn how target safety assessments (TSAs) are used to determine the potential consequences of modulating a target and provide options on how to assess those risks. Experts will describe how we derive relevant insights from the vast amount of publicly available information to provide clients with a focused assessment of key risks, tailored for each individual project. With over 140 publications in peer-reviewed journals, she is former president of the British Toxicology Society, former president of EUROTOX, former secretary to SOT, Past President of the Academy of Toxicological Sciences and a member of the Health and Environmental Sciences (HESI) board.
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