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25 Feb 2021Ended

A New Platform for Clinical Gene Editing of iPSCs to Make Clonal Cell Banks

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upto 100
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Feb 2021

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However, somewhat analogous to monoclonal antibodies 20 years ago, the editing and single-cell cloning of stem cells has, up until now, largely .. Read more been a black art reserved for experts. There is also great variation between groups and labs. Stem cells are inherently very sensitive to fluorescence-activated cell sorting (FACS) and culture conditions and their viability is typically poor when cloned. Solentim now presents a platform combination of instrumentation (the VIPS) and soluble matrix (MatriClone, based on laminin) for the high-efficiency, high-viability single-cell cloning of iPSCs to form the Master Cell Bank. This includes an industry-leading clonality documentation package to support future investigational new drugs (INDs). Most current instrumentation for stem cell isolation and cloning is only suitable for use in a research environment. Solentim realizes the need for cell therapy customers to implement systems in research now which can then be replicated and used in their clinical manufacturing.

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