19 Apr 2021Ended

Mechanistic Modelling in Early Stage Chromatography Process Development for Improving Process Efficiency and Productivity


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Apr 2021


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This webinar provides an overview of current process innovation challenges and needs. The presenter identified that computational mechanistic .. Read more modelling can be used to simulate chromatographic process performance and process optimization. The webinar concludes a comparative analysis between empirical and mechanistic modeling and provide the insights of balance needs for both approaches. Yuyi Shen is the associate director and head of process development & manufacturing at Bolt Biotherapeutics. She served scientific leadership roles in process development and manufacturing science department at various biotech companies including XOMA, Bayer and BioMarin and Grifols. She holds a PhD degree in Chemical Engineering from University of California, Davis. She had solid trouble shooting and problem-solving skills and encouraging contract manufacturer to deliver with high efficiency and better quality under accelerated timeline.

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