18 - 19 May 2021Ended

Chemovar characterization using Time of Flight Mass Spectrometry


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May 2021


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Cannabis species like C. sativa L. are complex plants synthesizing more than 500 identified chemicals. Chemotype identification of cannabis strains .. Read more is related to cannabinoid content such as high ∆9-tetrahydrocannabinol or cannabidiol or both. However, stain identifications like Cannabis sativa L. or by chemotype are much less relevant for contemporary cannabis due to decades of interbreeding and the complexity of the plants and their secondary metabolomes. More recently, the concept of chemovars has been introduced. Chemovars consider cannabinoid, terpene, and flavonoid chemical profiles as chemical markers for a better overall characterization of the plant. A primary analytical methodology for chemovar identification is quadrupole time of flight mass spectrometry (qTOF) which offers high resolution accurate mass information for feature identification, structure elucidation, and annotation. In this presentation, we will demonstrate proof of principle for chemovar identification using qTOF with cannabis and hemp extracts and demonstrate how bioinformatic software is used to turn the raw information into knowledge.

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Agilent Technologies

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