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The SCI/RSC symposium on kinases will feature plenary lectures and case studies on emergent and successful kinase inhibitor programs. Topics include new screening approaches, brain penetrant inhibitors, and kinase inhibition for immuno-oncology. The event is for scientists and drug discovery community members.

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Medical & Pharma Science & Research

Timings 09:00 AM-06:00 PM (expected) Not Verified	Entry Fees Check Official Website
Estimated Turnout 100 - 500 Delegates Based on previous editions	Event Type Conference
Editions May 2023 +1 more edition Frequency Biennial Next edition likely in May 2025	Official Links WebsiteContacts Report Error Claim this event
Organizer Queries about the event? Ask Organizer Society of Chemical Industry UK272 Total Events

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Schedule & Agenda

Tue, 09 May 09:00 AM - 09:35 AM	Rational practical approaches for the efficient identification and optimisation of inhaled kinase inhibitors, Simon Peace, GlaxoSmithkline, UK
Tue, 09 May 09:30 AM - 10:00 AM	Registration and refreshments
Tue, 09 May 09:35 AM - 10:10 AM	Discovery and optimisation of potent, slow-dissociating inhaled PI4KB inhibitors, Sophie Bertrand, GSK, UK
Tue, 09 May 10:00 AM - 10:05 AM	Opening remarks
Tue, 09 May 10:05 AM - 10:45 AM	Keynote presentation: Protein editing using small molecules, Amit Choudhary, Broad Institute, USA
Tue, 09 May 10:10 AM - 10:45 AM	Refreshments, exhibition and posters
Tue, 09 May 10:45 AM - 11:15 AM	Structure-based lead optimization of orally bioavailable HPK1 inhibitors, Bryan Chan, Genentech, USA
Tue, 09 May 10:45 AM - 11:20 AM	Focal adhesion kinase: mechanistic insights as guide for allosteric targeting, Daniel Lietha, CIB-CSIC, Spain
Tue, 09 May 11:15 AM - 11:45 AM	Refreshments, exhibition and posters
Tue, 09 May 11:20 AM - 11:55 AM	The discovery of new inhibitors of cKIT for the treatment of GIST, Andreas Blum, Merck KGaA, Germany
Tue, 09 May 11:45 AM - 12:20 PM	Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer, Antonio Ricci, Roche, Switzerland
Tue, 09 May 11:55 AM - 12:30 PM	Short talks
Tue, 09 May 12:20 PM - 12:55 PM	Using generative AI for drug discovery: Scalable 3D AI target discovery and design of potent and selective kinase inhibitors, Chris Radoux, Exscientia, UK
Tue, 09 May 12:30 PM - 01:40 PM	Lunch, exhibition and posters
Tue, 09 May 12:55 PM - 02:00 PM	Lunch, exhibition and posters
Tue, 09 May 01:40 PM - 02:15 PM	Total inhibition of SRC kinase activity and scaffolding properties by a Type 1.5 inhibitor , Asier Unciti-Broceta, University of Edinburgh
Tue, 09 May 02:00 PM - 02:35 PM	Brain penetrant protein kinase inhibitors as potent modulators of TDP-43: a new hope for ALS therapy? , Ana Martinez, CSIC, Spain
Tue, 09 May 02:15 PM - 02:50 PM	Optimisation of Mer/Axl kinase inhibitors for immuno-oncology, William McCoull, AstraZeneca, UK
Tue, 09 May 02:35 PM - 03:10 PM	Structure-based optimisation of CNS penetrant MSK-1 inhibitors, Anne Valade, UCB, Belgium
Tue, 09 May 02:50 PM - 05:30 AM	Closing remarks
Tue, 09 May 03:10 PM - 03:30 PM	Flash poster session
Tue, 09 May 03:30 PM - 04:00 PM	Refreshments, exhibition and posters
Tue, 09 May 04:00 PM - 04:35 PM	Inhibition of TYK2 via the pseudokinase: the discovery of deucravacitinib , Ryan Moslin, Bristol-Myers Squibb, USA
Tue, 09 May 04:35 PM - 05:10 PM	The importance of conformation in the structure-based design of selective CaMK1 inhibitors, Sam Butterworth, University of Manchester, UK
Tue, 09 May 05:10 PM - 05:45 PM	Development of MAP4K4 inhibitors for the suppression of cardiac muscle cell death, Rehan Aqil, Domainex, UK
Tue, 09 May 05:45 PM - 09:00 AM	Network reception, exhibition and posters

Venue Map & Directions

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14-15 Belgrave Square, Belgravia, London SW1X 8PS
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SCI/RSC Symposium on Kinase Inhibitor Design

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Society of Chemical Industry